WANG Yan1a,1b,1c,2, CHEN Jinmei2, ZHENG Xiasheng1d, CHENG Jinle2
(1a. Research Center of Chinese Herbal Resource Science and Engineering; 1b. Key Laboratory of Chinese Medicinal Resource from Lingnan, Ministry of Education; 1c. Joint Laboratory of National Engineering Research Center for the Pharmaceutics of Traditional Chinese Medicines; 1d. Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China; 2. Key Laboratory of Technologies and Applications of Ultrafine Granular Powder of Chinese Medica, State Administration of Traditional Chinese Medicine, ZEUS Pharmaceutical group, Zhongshan 528437,China)
Abstract: In order to try out the research methods and techniques of modern polymer materials science, the characterization indexes and analysis methods of the characteristics of the ultrafine powder of Radix astragali were preliminarily determined. The characterization index and analysis of the characteristics of the ultrafine powder of Radix astragali method were studied. 10 batches of ultrafine powder of Radix astragali were prepared, and the factors affecting the particle size distribution, bulk density, specific surface area, angle of repose and color were determined. The methods for determining the powder index of ultrafine powder of Radix astragali were determined, and the powder indexes of the ultrafine powder of Radix astragali were established. The results show that the established methods for determining the particle size, specific surface area, bulk density, fluidity and color of the ultrafine powder of Radix astragali can be used for powder determination. The best particle size distribution of 10 batches of the ultrafine powder of Radix astragali is between 16.417～44.113 μm, the bulk density is 0.17～0.28 g/mL, the specific surface area is 1.644 8～2.509 8 m2/g, the average angle of repose is 48.87 °, and the range is between 87.22 and 89.57.
Keywords: Radix astragali; ultrafine powder; micromeritics
中图分类号：R284.1 文献标志码：A
文章编号：1008-5548(2019)04-0018-08
DOI:10.13732/j.issn.1008-5548.2019.04.003
收稿日期： 2019-01-15，修回日期：2019-03-18，在线出版时间：2019-04-29 14:03。
基金项目：广东省中智药业集团中药破壁饮片院士工作站项目，编号：2014B090905015
第一作者简介：王艳(1993—)，硕士研究生，研究方向为中药新药研发。E-mail:1051415383@qq.com。
通信作者简介：
成金乐(1962—)，教授，博士生导师，主要研究方向为创新中药研究与开发。E-mail:gdcjl9@126.com。
郑夏生(1987—)，副研究员，博士，主要研究方向为中药质量评价，药用植物功能基因。E-mail:zheng.x.s1987@163.com。
