Abstract：The effects of process parameters on the dispersion and stability of Ti O2 slurry during the mechanical wet grinding were studied by orthogonal experiments. The results show that the optimum process conditions for dispersing Ti O2 are as follows:3 000 r/min of grinding speed, 80 min of time, 0.2 mm of zirconium ball diameter, 9.5 of p H and mass ratio of zirconium ball to Ti O2 is 20:1. As-prepared Ti O2 slurry under optimal process conditions still maintain a good dispersion stability after 48 h. The average particle size of the titanium dioxide particles is 136.7 nm by counting 200 particles from the image of scanning electron microscopy (SEM) , which is consistent with the results of average particle size of 139.2 nm measured by laser particle size analyzer and the equivalent diameter of 134.2 nm measured by BET method. It shows that the titanium dioxide particles are single partile dispersed after grinding.

Keywords：titanium dioxide; wet grinding; single particle dispersed; particle diameter