WEI Zhiquan， HONG Ruoyu

Abstract：The preparation methods of micron-sized silica microspheres which include polymerization induced colloid aggregation, seeded growth, templating method, reverse emulsion and some other methods were reviewed. The preparation methods were evaluated through the performance of silica microspheres, and its development direction were also presented.It is put forward that the high performance silica microspheres prepared by sodium silicate and other cheap silicon feedstock instead of silicate ester are the research priorities in the future, uniform microspheres with bigger particle size can be prepared by adjusting the categories of solvent from seed growth method which will become the emphasis in the further study, and the porous structure of microspheres prepared by polymerization induced colloid aggregation can be adjusted by templating method in order to obtain well-ordered mesoporous microspheres with high mechanical strength, high purity, as well as high specific surface area, which can be used in high-performance chromatographic column, biocatalysis and other fields.

Keywords: silica; micron-sized microspheres; preparation; review