Li Jinsong

（Institute of M icrobiology and Epidemiology．Beijing100071）

Abstract

Abstract T he current advance in molecular biology of bioaerosol is mainly introduced．T he aerosols of proteins may be as a therapeutic drug for treating respiratory tract diseases and a vaccine antigen for introducing immunity of the respiratory tract mucous membrane．Aerosols that how to drive respirable-sized funcitional proteins and maintaining proteins activity are a key．T herapeutic DNA molecules and gene immunity are a new research field．T he technology for aerosolized DNA plasmid and transformation and expression after inhalation are of great interest．T he PCR technique has potential for use in detection of low concentrations of bioaerosols．T he sensitivity of PCR assay is higher than other assay． So PCR assay for detecting airborne microorganisms is rapid and sensitive and can be used as an alternative method for air quality monitoring．

Keywords：aerosol；protein；therapeutic DNA；polymerase chain reaction

DOI：10.13732/j.issn.1008-5548.1999.03.005